Autoimmune Disease Research

Lupus, or systemic lupus erythematosus (SLE), is a complex autoimmune disease in which the immune system mistakenly targets healthy tissues, causing widespread inflammation and damage to organs and systems throughout the body. Though the exact cause remains unclear, it is believed to result from a combination of genetic, environmental, and hormonal factors. Our research focuses on unraveling these causes to develop more effective treatments and potentially a cure for this debilitating condition.

Type 1 diabetes is a lifelong autoimmune condition in which the immune system destroys insulin-producing beta cells in the pancreas, leading to a lack of insulin and an inability to regulate blood sugar levels. Our research aims to uncover the underlying genetic and immunological factors that trigger this autoimmune response, with the goal of developing treatments that can prevent or reverse the destruction of beta cells, and ultimately lead to better management or even a cure.

Rheumatoid arthritis (RA) is a chronic autoimmune disorder primarily affecting the joints, where the immune system attacks the synovium, the lining of the joints. This leads to persistent inflammation, pain, and eventual joint damage. Unlike osteoarthritis, which is caused by wear and tear, RA is driven by an immune response. Our research is centered on understanding the mechanisms behind this immune attack, aiming to discover targeted therapies that can slow or halt the progression of this disease.